A Final Attempt at Finding DnaA Boxes in E. coli
Learn that computational predictions, though powerful, can be inconclusive.
We'll cover the following...
We now make a final attempt to find DnaA boxes in E. coli by finding the most frequent 9-mers with mismatches and reverse complements in the region suggested by the minimum skew as ori. Although the minimum of the skew diagram for E. coli is found at position 3923620, we shouldn’t assume that its ori is found exactly at this position due to random fluctuations in the skew. To remedy this issue, we could choose a larger window size (e.g., ...