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Detour: Pitfalls of Assembling Double-Stranded DNA

Detour: Pitfalls of Assembling Double-Stranded DNA

Let’s observe some problems which occur while assembling double-stranded DNA.

We'll cover the following...

Handling reads in double-stranded DNA

To assemble real genomes, bioinformaticians must handle reads from both DNA strands without knowing in advance which strand each read comes from. To address this challenge, they first ...