Deamination

Understand how deamination affects the forward and reverse half-strands.

In the last section, we saw that as the replication fork expands, DNA polymerase synthesizes DNA quickly on the reverse half-strand but suffers delays on the forward half-strand. Notice that since the replication of a reverse half-strand proceeds quickly, it lives double-stranded for most of its life. Conversely, a forward half-strand spends a much larger amount of ...