Open Problem: Multiple Replication Origins in a Bacterial Genome
Learn about the details of multiple replication origins in a bacterial genome.
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Biologists long believed that each bacterial chromosome has only one ori. Wang et al., 2011 genetically modified E. coli by inserting a synthetic ori a million nucleotides away from the bacterium’s known ori. To their surprise, E. coli continued business as usual, starting replication at both locations!
Existence of bacteria having multiple oris
Following the publication of ...